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34 cases of nasal pathological features of round cell malignant tumors
Cancer cells showed round cells showed diffuse growth. The 5 cases of undifferentiated carcinoma, 3 cases of malignant lymphoma cells resemble (Fig. 5 ), diagnosis is difficult . Application of epithelial markers EMA and CK joint markers were positive, but negative for LCA and confirmed undifferentiated carcinoma. The 5 cases of olfactory neuroblastoma ,abercrombie outlet, tumor cells were small round or oval ,puma shoes, very little cytoplasm , some areas are typical or not typical of the daisy group structure. Of atypical cases , transmission electron microscopy is necessary , 3 patients in this group is difficult to diagnose , even if has been fixed in formalin , paraffin blocks of the conventional electron microscope can still press the producer, electron microscopy the cytoplasm of tumor cells with more Neurosecretory granule membrane 41 , to provide a reliable means of diagnosis -based . 2 patients in this group of embryonal rhabdomyosarcoma, scattered tumor cells and malignant lymphoma is difficult to identify, immunohistochemistry Myoglobin was positive , but negative for LCA , it is verifiable as embryonal rhabdomyosarcoma. Third, clinical and prognosis : The group of 34 round cell tumor in the nasal cavity , 2l cases of malignant lymphoma after radiation therapy and chemotherapy , surgical removal of the remaining tumors were used after the line of radiation therapy. Data show that : nasal non-Hodgkin's lymphoma , T -cell lymphoma and B -cell lymphoma,ed hardy swimwear, 5-year survival rates were 12.5% ??and 75 %, while the olfactory neuroblastoma is 5O ~ 60% L] J. Our data show 5-year follow-up survival rates were 11% , 83.3 % and 75 %, with similar reports in the literature base ,mbt cipo, B cell lymphoma and olfactory neuroblastoma slightly higher survival rate may indicate malignant B cells Lymphoma and olfactory neuroblastoma is low grade malignant tumor . We believe that nasal round cell tumors , these tumors often makes local ulcer or erosion ,gucci sito ufficiale, the small cells were round , toger with necrosis and inflammatory cell infiltration can be easily misdiagnosed . And clinicians need to contact at this time , repeatedly drawn , not easily diagnosed as inflammation , and when clinicians try to avoid the biopsy of necrotic tissue , tumor tissue taken delivery of deep pathological examination , immunohistochemical examination, generally can be confirmed.
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